Mark Gurarie yog tus kws sau ntawv ywj pheej, tus kws sau ntawv thiab tus kws qhia ntawv ib nrab sijhawm sau ntawv ntawm George Washington University.
Anita Chandrasekaran, MD, Master of Public Health, tau lees paub los ntawm Pawg Thawj Saib Xyuas Kev Noj Qab Haus Huv thiab Rheumatology, tam sim no ua haujlwm ua tus kws kho mob rheumatologist ntawm Hartford Healthcare Medical Group hauv Connecticut.
Gel-One (cross-linked hyaluronate) yog ib qho kev kho mob rau lub hauv caug osteoarthritis (OA).Qhov no yog ib qho kev txhaj tshuaj uas pab tswj qhov mob.
Nws yog muab los ntawm cov protein (hyaluronic acid) muab rho tawm los ntawm nqaij qaib combs lossis combs.Tib neeg lub cev ib txwm tsim cov protein no los lubricate pob qij txha.Nws lub luag haujlwm yog los kho cov qib ntawm cov protein no.
Gel-One tau pom zoo thawj zaug los ntawm US Food and Drug Administration (FDA) hauv xyoo 2001. Nws tsuas yog raug soj ntsuam hauv kev sim tshuaj thiab ua pov thawj tias muaj txiaj ntsig zoo hauv kev txo cov qhab nia mob ntev txog 13 lub lis piam, tab sis lwm cov ntsiab lus kawg, suav nrog kev txhav thiab lub cev. kev ua haujlwm, tsis muaj qhov sib txawv ntawm qhov sib txawv nrog cov placebo.
Tsis muaj kev kho kom tiav rau OA.Qhov kev kho no feem ntau tsuas yog ua tom qab sim lwm txoj hauv kev tswj hwm (xws li noj tshuaj lossis kho lub neej).
Zoo li txhua yam tshuaj, Gel-One txhaj tsis yog tsis muaj kev phiv thiab kev pheej hmoo.Yog tias koj muaj OA, nws tseem ceeb heev kom paub ntau npaum li qhov ua tau txog koj txoj kev npaj kho mob.
Gel-One yog tsim rau hauv caug OA, uas yog tus cwj pwm los ntawm kev sib koom ua ke thiab tsim kua muag, uas ua rau mob.OA yog hom kab mob feem ntau ntawm kev mob caj dab, thiab txawm tias nws tuaj yeem cuam tshuam rau leej twg, nws feem ntau tshwm sim rau cov neeg laus dua 65 xyoo.
Ua ntej, thaum lwm yam kev kho mob (xws li noj cov tshuaj uas tsis yog-steroidal anti-inflammatory tshuaj (NSAID) lossis kev kho lub cev) tsis zoo, Gel-One yuav raug sim.Txij li OA yog ib qho kab mob loj zuj zus tuaj thiab hloov tsis tau, txawm tias kev phais yuav yog ib qho kev xaiv, kev kho mob feem ntau txhais tau tias tswj cov tsos mob.Qhov kev txhaj tshuaj no sawv cev rau kev kho mob ntxiv.
Ua ntej txiav txim siab Gel-One txhaj tshuaj raws li kev kho mob, kev kuaj mob ntawm OA yog qhov tseem ceeb.Yuav ntsuas qhov xwm txheej no li cas?Qhov no yog ib qho kev tawg sai:
Sib tham txog txhua yam tshuaj, tshuaj, thiab cov vitamins uas koj tab tom noj nrog koj tus kws kho mob.Txawm hais tias qee cov tshuaj ua rau muaj kev pheej hmoo me ntsis ntawm kev sib cuam tshuam, lwm yam tshuaj yuav raug contraindicated tag nrho los yog ua tib zoo xav txog seb cov txiaj ntsig thiab kev puas tsuaj ntawm kev kho mob ntau dua li koj qhov teeb meem.
Hyaluronic acid derivatives muag nyob rau hauv cov npe xws li Restylane, Juvéderm thiab Perlane yog lub ntsej muag fillers siv los du wrinkles los yog plump daim di ncauj.Zoo li cov pob qij txha, qib hyaluronic acid yuav txo qis nrog lub hnub nyoog, ua rau cov tawv nqaij sagging.Los ntawm txhaj cov tshuaj no rau hauv lub ntsej muag, daim tawv nqaij yuav firmer.
Tsis tas li ntawd, cov kws kho hniav yuav siv cov tshuaj pleev hyaluronic acid ua ib feem ntawm txoj kev kho mob rau cov pos hniav mob.Ntxiv nrog rau lwm yam kev kho mob, nws kuj tseem pab txo qhov mob ntawm cov chaw no thiab pab kho gingivitis, periodontitis thiab lwm yam teeb meem.
Kev txhaj tshuaj Gel-One tsuas yog siv los ntawm cov kws kho mob hauv tsev kho mob, thiab raws li tau hais los saum no, nws tsis pom zoo kom ua hom kev kho mob ntau dua ib zaug hauv caug.Nws tau ntim rau hauv lub khob ntim tshuaj ua ntej, ntim nrog 3 milliliters (mL) ntawm cov tshuaj, uas muaj 30 milligrams (mg) ntawm hyaluronic acid.
Seigaku Corporation, uas tsim Gel-One, thiab FDA hais tias nws tsis pom zoo kom siv ntau zaus lossis hloov cov tshuaj.Txawm li cas los xij, yog tias koj tsis paub meej, nco ntsoov tham txog cov tshuaj uas tsim nyog nrog koj tus kws kho mob.
Txawm hais tias kev tswj hwm thiab kev khaws cia nyob ntawm koj tus kws kho mob, nws tseem ceeb heev kom nkag siab tias qhov no yuav tsum zoo li cas.Kev siv Gel-One kom raug yog raws li hauv qab no:
Cov kev mob tshwm sim ntau dua ntawm Gel-One txhaj tshuaj yuav daws tau;Txawm li cas los xij, koj yuav tsum qhia rau koj tus kws kho mob paub yog tias muaj teeb meem no tshwm sim los yog tshwm sim.Lawv suav nrog:
Tom qab kev kho mob, thov ua tib zoo saib seb koj xav li cas.Yog tias koj xav tias koj xav tau kev pab, thov tsis txhob yig mus thov kev pab.
Cov tshuaj tiv thaiv hnyav rau Gel-One yog qhov tsawg thiab feem ntau yog tshwm sim los ntawm kev tsis haum tshuaj rau cov tshuaj.Yog tias koj ntsib ib qho xwm txheej hauv qab no, thov nrhiav kev pab tam sim:
Qhov laj thawj uas Gel-One feem ntau zam tau yog tias cov tshuaj tau tswj hwm los ntawm tus kws kho mob, yog li txo qis txoj hauv kev ntawm kev noj ntau dhau.Txij li nws feem ntau tsis muab ntau zaus (tsawg kawg ntawm tib lub hauv caug), qhov ua tau ntawm kev cuam tshuam tsis zoo ntawm cov tshuaj no thiab lwm yam tshuaj uas koj noj yog tsawg heev.
Txawm li cas los xij, nws yog ib qho tseem ceeb uas yog tias koj cov tawv nqaij tau ntxuav nrog cov tshuaj tua kab mob quaternary ammonium, koj yuav tsum tsis txhob txhaj tshuaj Gel-One.Cov tshuaj yuav ua rau cov kev daws teeb meem zoo li no.
Casale M, Moffa A, Vella P, thiab lwm yam Hyaluronic acid: yav tom ntej ntawm kev kho hniav.kev ntsuam xyuas.Int J Immunopathol Pharmacol.2016; 29(4):572-582.
Post lub sij hawm: Oct-19-2021