FRANKFURT, Lub teb chaws Yelemees–(BUSINESS WIRE)–Merz Therapeutics, tus thawj coj hauv thaj tsam ntawm neurotoxins thiab kev lag luam hauv Merz Group, thiab Teijin Pharma Limited, lub tuam txhab tseem ceeb ntawm Teijin Group txoj kev lag luam kho mob, sib koom tshaj tawm hnub no tias Teijin Pharmaceuticals tau yeej Ntxiv. Kev pom zoo los ntawm Nyiv Ministry of Health, Labor thiab Welfare (MHLW) siv Xeomin® (incobotulinumtoxinA) hauv 50, 100 lossis 200 units ntawm kev txhaj tshuaj intramuscular rau kev kho mob ntawm cov ceg qis.
Lower limb spasm yog ib qho tsos mob ntawm lub cev muaj zog neuron syndrome, uas feem ntau tshwm sim los ntawm cov leeg nqaij ntawm cov ceg tawv thiab kev zoo siab heev ntawm stretch reflex raws li ib qho kev mob stroke.Cov tsos mob tseem ceeb yog nyuaj rau kev taug kev ib txwm muaj thiab muaj kev pheej hmoo ntawm kev ntog vim lub cev tsis ruaj khov, kev ua haujlwm nyuaj lossis cuam tshuam hauv lub neej txhua hnub.Kev kho mob rau cov ceg spasms suav nrog kev kho lub cev thiab kev siv cov leeg ntawm qhov ncauj los yog cov kab mob neuromuscular blockers, xws li botulinum toxin type A.
Stefan Brinkmann, CEO ntawm Merz Therapeutics, tau hais tias: "Qhov kev pom zoo txuas ntxiv yog qhov tseem ceeb rau Merz Therapeutics thiab yog qhov tshwm sim ntawm peb txoj kev koom tes nrog Teijin Pharmaceuticals.Peb cia siab tias peb cov neeg koom tes yuav ua tiav qhov qhia txog qhov tseem ceeb spasticity rau cov kws kho mob thiab cov neeg mob Nyij Pooj. "
Dr. Stefan Albrecht, Senior Vice President of Global R&D, Merz Therapeutics: “Qhov kev nthuav dav daim ntawv lo hauv Nyij Pooj yog lwm qhov piv txwv zoo ntawm cov txiaj ntsig uas Xeomin ® muab rau ntau tus neeg mob tom qab mob stroke spasticity.Tam sim no cov kws kho mob tuaj yeem xaiv los kho tus mob qis thiab sab sauv sab sauv, lossis lawv tuaj yeem hloov tau raws li qhov xav tau Siv cov tshuaj ib leeg kom zoo.Peb txaus siab rau qhov kev ua tiav no, tshwj xeeb tshaj yog kev koom tes zoo nrog peb tus khub Teijin. "
Teijin Pharmaceutical Thawj Tswj Hwm Ichiro Watanabe tau hais tias: “Teijin Pharmaceutical muab ntau yam tshuaj, suav nrog kev kho mob pob txha thiab cov cuab yeej kho mob, xws li lub suab nrov nrawm nrawm kho pob txha rau cov neeg mob uas muaj kab mob musculoskeletal.Hauv kev teb rau cov kev hloov pauv ntawm pej xeem thiab kev paub txog kev noj qab haus huv ntxiv, Peb tab tom tsim cov tshuaj tshiab thiab cov kev daws teeb meem zoo, suav nrog kev ua kom muaj kev vam meej hauv zej zog.Teijin Pharmaceuticals tseem txhawb nqa kev txhim kho lub neej zoo (QOL) ntawm cov neeg mob los ntawm kev muab cov kev kho mob tshiab rau cov kab mob uas tsis muaj kev xav tau.”
Xeomin® zoo kho cov hlab ntsha peripheral cholinergic los ntawm kev ua kom tsis muaj zog ntawm cov leeg leeg, thiab txo cov leeg nro los ntawm inhibiting kev tso tawm ntawm cov neurotransmitter hu ua acetylcholine.Lub siab huv neurotoxin yog tib yam khoom muaj nyob hauv Xeomin®.Nws yog tsim los ntawm kev tshem tawm complex proteins los ntawm hom A botulinum toxin uas tsim los ntawm Clostridium botulinum siv cov purification technology tsim los ntawm Merz Pharma GmbH & Co. KGaA.Qhov tsis muaj cov proteins nyuaj tso cai rau Xeomin® kom txo qis kev tsim cov tshuaj tiv thaiv kab mob uas tuaj yeem txo qhov ua tau zoo.Kev txhim kho tseem ceeb hauv plantar flexor hloov kho ashworth scale (MAS) tau pom nyob rau hauv theem III kev sim tshuaj hauv Nyiv.
Xeomin® yog muab faib los ntawm Merz Pharmaceuticals GmbH nyob rau hauv ntau tshaj 70 lub teb chaws thiab yog siv los kho cov neeg mob uas muaj lub sab sauv qaum spasm, cervical dystonia, blepharospasm los yog salivation ntau heev.Teijin Pharmaceuticals tau kos npe rau daim ntawv tso cai tshwj xeeb thiab kev cog lus sib koom ua ke rau Xeomin® hauv Nyij Pooj nrog Merz hauv 2017, thiab pib muag tshwj xeeb ntawm Xeomin® thaum Lub Kaum Ob Hlis 2020 tom qab tau txais kev pom zoo los ntawm Ministry of Health, Labor thiab Welfare (MHLW) ntawm Nyiv.Raws li Merz's Phase III kev kuaj mob hauv Nyij Pooj, qhov kev pom zoo tshiab tau txais ntxiv tau hloov qee qhov kev pom zoo.
Feem ntau, rau cov neeg laus, Xeomin® yuav tsum tau txhaj rau hauv ntau cov leeg nqaij.* Cov koob tshuaj ntau tshaj plaws rau ib qho kev tswj hwm yog 400 units, tab sis nws yuav tsum raug txo kom tsawg rau qhov tsawg kawg nkaus raws li hom thiab tus naj npawb ntawm lub hom phiaj tonic leeg.Yog tias cov nyhuv ntawm koob tshuaj yav dhau los txo qis, tso cai rov ua dua.Lub sijhawm noj tshuaj yuav tsum yog 12 lub lis piam lossis ntev dua, tab sis nws yuav raug luv rau 10 lub lis piam nyob ntawm cov tsos mob.
* Myotonic: gastrocnemius (medial taub hau, lateral taub hau), soleus, posterior tibialis, flexor digitorum longus, thiab lwm yam.
Merz Therapeutics yog kev lag luam ntawm Merz Pharmaceuticals GmbH nplooj siab los txhim kho lub neej ntawm cov neeg mob thoob ntiaj teb.Nrog nws cov kev tshawb fawb tsis tu ncua, kev txhim kho thiab kev coj noj coj ua tshiab, Merz Therapeutics sib zog ua kom tau raws li cov neeg mob xav tau thiab ua tiav cov txiaj ntsig zoo dua.Merz Therapeutics nrhiav kom tau raws li cov kev xav tau tshwj xeeb ntawm cov neeg uas muaj kev cuam tshuam ntawm kev txav mus los, kab mob hauv lub paj hlwb, kab mob siab, thiab lwm yam kev noj qab haus huv uas cuam tshuam rau lub neej zoo ntawm cov neeg mob.Merz Therapeutics yog lub hauv paus hauv Frankfurt, lub teb chaws Yelemees, nrog cov chaw ua haujlwm sawv cev hauv ntau dua 90 lub teb chaws, thiab North American ceg hauv Raleigh, North Carolina.Merz Pharmaceuticals GmbH yog ib feem ntawm Merz Group, ib lub tuam txhab ntiag tug hauv tsev neeg uas tau cog lus los tsim kev tsim kho tshiab uas ua tau raws li cov kev xav tau ntawm cov neeg mob thiab cov neeg siv khoom rau ntau tshaj 110 xyoo.
Teijin (Tokyo Tshuag Txauv Code: 3401) yog ib pab pawg neeg siv tshuab thoob ntiaj teb uas muab cov kev daws teeb meem zoo tshaj plaws hauv thaj tsam ntawm ib puag ncig tus nqi;kev nyab xeeb, kev ruaj ntseg, thiab txo kev puas tsuaj;nrog rau kev hloov pauv pej xeem thiab kev paub txog kev noj qab haus huv ntxiv.Teijin yog thawj zaug tsim nyob rau hauv 1918 raws li thawj rayon chaw tsim tshuaj paus nyob rau hauv Nyiv, thiab tam sim no tau tsim mus rau hauv ib tug tshwj xeeb kev lag luam npog peb lub lag luam tseem ceeb: cov ntaub ntawv ua tau zoo xws li aramid, carbon fiber thiab composite cov ntaub ntawv, raws li zoo raws li resin thiab yas ua, Zaj duab xis , polyester fiber ntau thiab cov khoom ua tiav;kev kho mob, suav nrog cov tshuaj thiab cov khoom siv kho mob hauv tsev rau cov pob txha / pob qij txha, cov kab mob ua pa, thiab cov kab mob plawv / metabolic, kev saib xyuas neeg mob thiab kev kho mob ua ntej;thiab IT, suav nrog kev kho mob, koom haum thiab B2B cov kev daws teeb meem rau pej xeem, nrog rau cov software ntim khoom thiab B2C cov kev pabcuam online rau kev lom zem digital.Raws li tau hais hauv cov lus tshaj tawm "Human Chemistry, Human Solutions", Teijin tau mob siab rau nws cov neeg koom tes thiab lub hom phiaj los ua ib lub tuam txhab uas txhawb nqa lub neej yav tom ntej.Cov pab pawg muaj ntau dua 170 lub tuam txhab thiab muaj kwv yees li 20,000 tus neeg ua haujlwm hauv 20 lub teb chaws / cheeb tsam thoob ntiaj teb.Hauv lub xyoo nyiaj txiag xaus rau lub Peb Hlis 31, 2021, Teijin tshaj tawm kev muag khoom ntawm 836.5 billion yen ($ 7.7 billion) thiab tag nrho cov cuab tam ntawm 1.036.4 billion yen ($ 9.5 billion).
Post lub sij hawm: Sep-10-2021